If your goal is reducing removable-media data leakage on shared or office PCs, the best USB port lock software should block unknown devices, allow approved ones, and support clear policy control.
1. You want USB device policy rather than encrypted storage.
2. You need trusted-device rules for approved company drives.
3. You want a practical way to reduce copy-out risk on Windows PCs.
Use USB Encryption if the drive itself needs password-protected storage encryption. Use File Lock Pro if you only want to lock selected folders rather than control the USB channel.
For most users searching "best USB port lock software," GiliSoft USB Lock is the better match when the real requirement is device control, removable-media restrictions, and trusted-device policy.